Osteogenesis Imperfecta

Also known as: OI.

What is osteogenesis imperfecta?

Osteogenesis imperfecta is a genetic disorder present at birth that causes brittle bones that break easily. Several different related medical conditions fall under the umbrella term of osteogenesis imperfecta.

What causes osteogenesis imperfecta?

Osteogenesis imperfecta is a genetic condition caused by a gene mutation. It’s often hereditary and can be passed down from parents to their children.

What are the symptoms of osteogenesis imperfecta?

Brittle bones and frequent fractures are the primary symptoms of osteogenesis imperfecta. It can range in severity from mild to severe. Other complications can include hearing problems, breathing problems, a blue tint to the eyes, short stature and other complications.

What are osteogenesis imperfecta care options?

Treatment is focused on managing the symptoms of osteogenesis imperfecta. This might include steps such as physical therapy, medication, exercises and surgery. Some with the disease might require braces or wheelchairs.

Reviewed by: Michael A Tidwell, MD

This page was last updated on: March 20, 2019 04:12 PM

Patient Success Stories

Patient of the Month: Alexis

Alexis has suffered more fractures in her short life of life than what the average person will in their entire lifetime. This is because Alexis has a very rare disease called osteogenesis imperfecta, also known as "brittle bone disease."  Read More.

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