Drug-induced Liver Disease

Also known as: drug-induced hepatitis.

What is drug-induced liver disease?

If use on over-the-counter medications, prescriptions medications, herbs and supplements or illegal drugs ultimately leads an individual to develop liver problems, this is known as drug-induced liver disease. These diseases can vary widely in nature and severity.


What causes drug-induced liver disease?

Certain drugs, whether they be over-the-counter, prescription, or illicit, can directly damage the tissue of the liver. Over time, this damage leads to liver disease. Certain drugs can also be transformed by the liver into chemicals that are toxic to the liver, also causing damage that leads to drug-induced liver disease.


What are the symptoms of drug-induced liver disease?

Drug-induced liver disease can cause jaundice (yellowing of the skin and eyes), itchy skin, swelling of the abdomen or legs, kidney problems, easy bruising, gastrointestinal bleeding, mental problems, liver failure and various other symptoms.


What are drug-induced liver disease care options?

Stopping use of the offending drug is the most important treatment for drug-induced liver disease. Certain medications can help to minimize the amount of damage done to the liver and prevent it from worsening. In cases of advanced liver disease, a liver transplant might be a viable option.


Reviewed by: Shifra A Koyfman, MD

This page was last updated on: 2/3/2018 4:28:23 PM

From the Newsdesk

Medical Mission to Algeria Helps Children in Need of Spinal Surgeries
03/06/2018 — A group of children in Algeria who underwent complex surgeries as part of a 2016 U.S.-sponsored medical mission have many reasons to celebrate, and can do so with better movement of their limbs.
Outpatient Surgery Success Story
02/28/2018 — Caludell noticed that 6 of her 11 children had belly buttons that stuck out, and they seemed to become more pronounced around the time they entered kindergarten. When her daughters started to become self-concious about how their belly buttons looked, Claudell was able to schedule all 6 umbilical repair surgeries on the same day at the Miami Children's  Ambulatory Surgery Center.