Also known as: PJS.
What is Peutz-Jeghers syndrome?
Peutz-Jeghers syndrome is a genetic disorder that causes affected individuals to develop polyps in their intestines. Polyps are small growths of tissue that are typically non-cancerous, but they can increase the risk of cancer developing over time. Other symptoms can also occur with Peutz-Jeghers syndrome.
What causes Peutz-Jeghers syndrome?
In many cases, Peutz-Jeghers syndrome is due to a genetic mutation that is passed along from parents to their children. Other times, the disease occurs sporadically for unknown reasons.
What are the symptoms of Peutz-Jeghers syndrome?
In some cases, the polyps can lead to abdominal pain, cramping, vomiting and bloody stools. Symptoms such as clubbed fingers or toes and freckles or spots on the faces of infants can also occur with Peutz-Jeghers syndrome.
What are Peutz-Jeghers syndrome care options?
Individuals with Peutz-Jeghers syndrome are often under observation due to the cancer risk associated with the condition. The polyps can be removed surgically if they become problematic.
Regular follow up with a pediatric gastroenterologist is essential to screen for early polyps with various technologies including endoscopy.
Reviewed by: Ziad A Khatib, MD
This page was last updated on: 5/24/2018 9:30:51 AM
Camp U.O.T.S. is an annual weeklong, overnight camp for children with cancer and blood disorders who are treated at Nicklaus Children’s Hospital.
Learn more and register
From the Newsdesk
More than two dozen children attended the Bear Hug camp at Nicklaus Children's last week. This day camp is for siblings of pediatric cancer patients to encourage socialization among peers and help them gain insight on their siblings' care journey.
On this very same day nine years ago, Daniella Alvarez was diagnosed Teratoid Rhabdoid Tumor (ATRT), a rare and aggressive type of brain cancer. The news came on June 26, 2009, her second birthday. Daniella endured years of brain surgeries, aggressive chemotherapies, radiation, imaging scans, multiple visits to intensive care at Nicklaus Children’s Hospital. She is now cancer free thanks to a pediatric clinical trial made possible through research funding.