Morquio Syndrome

Also known as: MPS IV.

What is Morquio syndrome?

Morquio syndrome is a genetic disorder where a baby has trouble breaking down sugar chains in the body. This prevents the body from getting the required nutrients for the development of things like skin, tendons, ligaments, bone, cartilage and other tissues. It can lead to a number of potential complications.

What causes Morquio syndrome?
Morquio syndrome is a hereditary condition that is passed down from parents to children.

What are the symptoms of Morquio syndrome?
The problems tied to Morquio syndrome lead to symptoms such as curved spine (scoliosis), joints that move more than they should (hypermobility), neck that moves more than it should (instability), a large head, short stature, wide teeth, heart and vision problems and a number of other complications.

What are Morquio syndrome care options?
Morquio syndrome cannot be cured. The treatments can vary widely depending on what parts of the body are affected. Treatment may include physical therapy, occupational therapy, counseling, surgery and other treatments.

Reviewed by: Stephen Graham George Jr., MD

This page was last updated on: 8/13/2018 10:41:47 AM

From the Newsdesk

What is the Personalized Medicine Biobank?
The Nicklaus Children's Hospital biobank and tissue repository is an essential resource for personalized medicine research efforts, enabling the study of both health and disease over time. The Biobank collects samples and health information from volunteers, regardless of health history. Once a participant becomes part of the Biobank, he or she contributes to ongoing health research. We partner with Sanford Health, a national leader on specimen storage, management and integration with participant health information.
What is Genetic Testing?
Dr. Parul Jayakar discusses genetic testing for family planning. Learn more at nicklauschildrens.org/Genetics