The Brain Institute

Research Initiatives and News

To ensure that the Nicklaus Children’s Hospital Brain Institute remains solidly at the forefront in its field, a team of neuroscientists has forged active collaborations with universities and industry partners to advance care.

Brain Function and Neuromodulation

Several scientists associated with the Brain Insitute  are developing advanced neuroengineering techniques to study functional dynamics and identify the most subtle abnormalities underlying neurological disorders. These studies will facilitate diagnoses, promote neuromonitoring in the ambulatory as well as critical care setting and enhance neurosurgical guidance. They also support the development of novel neuromodulation therapies.

Non-Invasive Neurological Therapies

The Brain Institute has begun research on a revolutionary technology for non-invasive, effective and safe treatment of a large variety of common or devastating brain disorders. It will allow:
  • Targeted focal ablations of brain tissue with high precision. Benefits compared to conventional surgery include outpatient  surgery avoiding the discomfort and risks including  the wound, trauma to normal brain tissue, bleeding, infection, pain  and prolonged recovery.
  • Targeted therapeutics by selective opening of the blood-brain-barrier to achieve greater concentrations of medications at specific brain sites to enhance efficacy with minimal side effects on surrounding brain or rest of the body.


The Brain Institute has been involved in research on genomic markers to optimize the selection of medical therapies, enhancing their efficacy and safety. The initial focus of this personalized medicine strategy is on ion-channel epilepsies and brain tumors.

Related News

Pediatric Neurosurgeon and Chief of Surgery for Nicklaus Children’s Passes Away

The medical staff, employees and volunteers of Nicklaus Children’s Hospital mourn the passing of our esteemed Dr. Sanjiv Bhatia, a longstanding leader and dedicated champion for children with complex medical conditions and their families.


New Device Helps Children with Drug-Resistant Epilepsy Manage Seizures

Grant is the first pediatric patient in South Florida to utilize the SenTiva VNS device, which is currently the smallest and lightest responsive therapy for epilepsy available on the market. The device, used in combination with epilepsy medications, has been shown to be effective in reducing seizure frequency and duration. 


Duchenne Regional Family Summit

CureDuchenne Cares and The Nicklaus Children’s Hospital Brain Institute hosted a free educational and social event for Duchenne family and caregivers. Attendees were able to learn about important DMD care topics, share their practical advice and connect with other families.


Autism Spectrum Disorder Report on Global and United States Market Analysis And Industry Overview Report 2017-2022

The market research report provides an in-depth analysis of the major AUTISM SPECTRUM DISORDER industry leading players along with the company profiles and strategies adopted by them.


Did Oxygen Therapy Really 'Reverse' Child's Brain Damage? Experts Are Skeptical

Eden Carlson experienced brain damage after she nearly drowned in a swimming pool. A controversial report claims that oxygen therapy reversed her brain damage, but experts are very skeptical.


Deadly Kiss: Can a Baby Contract a Lethal Virus from a Cold Sore?

A stock photo of a man kissing a baby.


Epilepsy Treatment

If you treat patients who live with epilepsy, this app is designed for you. Conceived and written by 2 pediatric neurologists practicing at Miami Children's Hospital in Miami, Florida


Boxers, MMA fighters may face long-term harm to brain: study

There's been a great deal of attention paid lately to the potential lasting damage of head blows suffered by professional football players.


Charlie Gard controversy: Why a baby’s head size matters

In a court hearing on Thursday (July 13), the parents of Charlie Gard, the critically ill baby in Britain, were at odds with their son’s hospital over a seemly straightforward fact: The size of their baby’s head.


Researchers Find New Hope for Children with Neurofibromatosis

Dr. Ziad Khatib, pediatric neuro-oncologist, discusses treatments for children with fibromatosis in this WPLG Local 10/ segment.


Dr. Roberto Tuchman to Address Autism Innovations & Global Impact at International Conference

Dr. Tuchman to discuss Google, Facebook, FaceTime and the Eletric Developing and Social Brain.


Dr. Michael Duchowny Honored with The Children's Trust David Lawrence Jr. for Children Award

Dr. Michael Duchowny is the receipient of the prestigious The Children's Trust David Lawrence Jr. for Children Award which honors individuals and programs that have reached the highest levels of excellence and achievement, their community partners and the families they have helped.


Pediatric Spasticity - New treatments mean better outcomes for all children and their parents

Dr. Toba Niazi specializes in the surgical treatment of children with brain and spinal cord tumors, and children with cerebral palsy, hydrocephalus, spasticity, vascular malformations, craniocervical and spinal pathologies and movement disorders.


Brain Institute doctors honored at Camp Boggy Creek‬ for their commitment to helping children with epilepsy

Congratulations to Dr. Ian Miller and Patricia Dean, ARNP, CNR, RN, who were honored last week at ‪‎Camp Boggy Creek‬ for their commitment to helping children with ‪‎epilepsy‬.


Rare Diseases Day

Patients and families treated by the Nicklaus Children's Brain Institute came together on "Rare Diseases Day" for the launch of a family advisory committee to support families of children with rare diseases. 


The Brain Institute's 2015 Epilepsy Surgery Reunion

Patients and families enjoyed lunch, and fun filled activities including a visit to Jungle Island.


Hydrocephalus Cases Receive Less Invasive Treatment Solutions at Nicklaus Children's Hospital

Pediatric neurosurgeon Dr. Sanjiv Bhatia helps lead the way with sustainable care that improves and saves young patient lives.


Haiti Hydrocephalus Project

In 2003 a team of medical volunteers, led by pediatric neurosurgeon Dr John Ragheb, traveled to Haiti to perform surgery for children with hydrocephalus. Hydrocephalus is one of the most common treatable causes of neurological disability and death in the developing world.


Related Press Releases

Eminent Pediatric Neurosurgeon Gregory W. Hornig, MD, Joins Nicklaus Children's Hospital

Eminent pediatric neurosurgeon Gregory W. Hornig, MD, has joined the Division of Pediatric Neurosurgery at Nicklaus Children’s Hospital’s Brain Institute and Pediatric Specialists of America (PSA), the multispecialty group practice of Nicklaus Children’s Health System.


Nicklaus Children’s Comprehensive Epilepsy Center Receives NAEC Accreditation

The Nicklaus Children's Hospital Comprehensive Epilepsy Center has received accreditation by the National Association of Epilepsy Centers (NAEC) as a level 4 epilepsy center. Level 4 epilepsy centers have the professional expertise and facilities to provide the highest level medical and surgical evaluation and treatment for patients with complex epilepsy.


Nicklaus Children’s Hospital Performs the World’s First Focused Ultrasound Surgery on Hypothalamic Hamartoma Tumor in Epilepsy Patient

A multidisciplinary clinical team at Nicklaus Children’s Hospital used magnetic-resonance guided focused ultrasound to ablate a centrally located brain tumor in a young patient experiencing tumor-associated seizures.


Sanford Health and Nicklaus Children’s Hospital Collaborate to Sequence Genes

Sanford Health and Nicklaus Children’s Hospital will sequence the genes of nearly 1,000 Latino and Hispanic people in an effort to better understand the health needs of those populations.


Nicklaus Children's Moves Patients into its New Advanced Pediatric Care Pavilion

The Advanced Pediatric Care Pavilion, a six-story, state-of-the-art bed tower now houses the hospital's three intensive care units, the neurology-neurosurgery unit and a cardiac intensive care unit, among other enhancements.


Nicklaus Children's Hospital Pediatric Specialty Services Again Ranked Among the Best in the Nation

Eight subspecialty programs of Nicklaus Children’s Hospital, part of Miami Children’s Health System, are again ranked among the best in the nation, according to U.S.News & World Report’s 2016-17 “Best Children’s Hospitals” rankings, posted online today. 


Nicklaus Children's Opens Subspecialty Clinic in Aventura

The Nicklaus Children's Aventura Care Center is the newest ambulatory location, offering consultations with pediatric subspecialists and diagnostic services.


Sixty-one Physicians on Nicklaus Children's Hospital Medical Staff Make Prestigious 2015-2016 Best Doctors in America® List

Only five percent of doctors in America earn this prestigious honor, decided by impartial peer review. 


Nicklaus Children's Hospital Pediatric Specialty Services Again Ranked Among the Best in the Nation

According to U.S.News & World Report’s 2015-16 “America’s Best Children’s Hospitals” rankings, seven subspecialty programs of Nicklaus Children’s Hospital, part of Miami Children’s Health System, are once again ranked among the best in the nation.


Brain Institute Clinicians Present Epilepsy Findings at Dravet Syndrome Medical Conference

Nicklaus Children's Hospital, formerly Miami Children's Hospital, Clinicians Present Epilepsy Findings at Dravet Syndrome Medical Conference


Miami Children’s Hospital Brain Institute is Region’s First in Using Minimally Invasive Technique for Epilepsy Surgery in Children

Epilepsy specialists at Miami Children’s Hospital are the first in the Southeast--and the second in the nation-- to offer minimally invasive laser surgery for children with seizures that don’t respond to anticonvulsant medications.


Miami Children’s Hospital Affiliation to Benefit Russian Children with Epilepsy

The Miami Children’s Hospital Global Health Services program has formed an affiliation with the Moscow Center for Pediatric Craniofacial Surgery and Neurology in Moscow, Russia. Through the initiative, experts at Miami Children’s Hospital are collaborating with their Moscow counterparts to advance surgical care for Russian children with medically resistant epilepsy.


Russian Physicians Visit Miami Children's Brain Institute

Neurologists from Moscow Pediatric Center of Craniofacial Surgery and Neurology, and Russian State Medical University are visiting Miami Children's Brain Institute.