Pigmented Villonodular Synovitis

Also known as: PVNS.

What is pigmented villonodular synovitis?

PVNS is rare, benign (non-cancerous, non-spreading) slowly growing tumor of the synovium. The synovium is a layer of tissue that lines joints and tendons of the body. PVNS is frequently found in the knee or hip joint.
 

What causes pigmented villonodular synovitis?

The precise cause of the disease is unknown, however some gene mutations have been identify associated with PVNS.

What are the symptoms of pigmented villonodular synovitis? 
Pain and swelling are common-other symptoms include stiffness, joint instability, trouble moving the joint with locking or catching of the joint.

What are pigmented villonodular synovitis care options? 
Surgery to remove excess tissue and repair any damage to the joints or tendons is the common treatment for pigmented villonodular synovitis. Recurrences may occur.

Reviewed by: Jack Wolfsdorf, MD, FAAP

This page was last updated on: 5/24/2018 9:31:53 AM

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April Patient of the Month: Lucky
04/09/2018 — Lucky started going to physical therapy when he was two because of the delays with sitting up and rolling over. His physical therapist noticed that the problem was not muscular but skeletal, a condition that she couldn't treat. The pediatrician told Janie and Greg, Lucky’s parents, about Nicklaus Children's Hospital. When Janie and Greg visited Nicklaus Children’s Hospital, they met Dr. Harry L Shufflebarger, Pediatric Spinal Surgery Director. He performed the necessary surgeries and now Lucky can enjoy a healthy life.
April Patient of the Month: Lucky
04/09/2018 — Lucky started going to physical therapy when he was two because of the delays with sitting up and rolling over. His physical therapist noticed that the problem was not muscular but skeletal, a condition that she couldn't treat. The pediatrician told Janie and Greg, Lucky’s parents, about Nicklaus Children's Hospital. When Janie and Greg visited Nicklaus Children’s Hospital, they met Dr. Harry L Shufflebarger, Pediatric Spinal Surgery Director. He performed the necessary surgeries and now Lucky can enjoy a healthy life.

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At age 10, Alessandra was diagnosed with scoliosis and started receiving treatment at Nicklaus Children’s Hospital. To view her inspiring story, visit mchf.org/alessandra.