Stickler Syndrome

Also known as: Stickler dysplasia, hereditary arthro-ophthalmopathy.

What is Stickler syndrome?

Stickler syndrome is a genetic disorder that commonly starts to show symptoms during infancy or childhood. The most common problems occur with the joints, hearing or vision. Unusual facial features are also characteristic of Stickler syndrome.

What causes Stickler syndrome?

Stickler syndrome is caused by genetic mutations. In most cases, the condition is hereditary and can be passed along from parents to children.

What are the symptoms of Stickler syndrome?

Common symptoms of Stickler syndrome include overly flexible joints, a curved spine (scoliosis), osteoarthritis, hearing problems, vision impairment, prominent eyes, a small nose and chin and cleft palate.

What are Stickler syndrome care options?

There is no cure for Stickler syndrome. Surgery and various forms of therapy can help to treat the symptoms that can occur.

Reviewed by: Paul A Cardenas, MD

This page was last updated on: 7/4/2018 9:33:15 AM

From the Newsdesk

Nicklaus Children's Hospital to offer new rapid genetic test
Nicklaus Children's Hospital will be one of a handful in the country to offer a fast turn-around on genome sequencing that can be a key to saving infants with rare and hard-to-diagnose genetic disorders. As seen on The Miami Herald.
Research Study: How your child's genetic makeup can impact the way he or she responds to certain medications
Enzymes are particularly important in the processing of medicines and drugs. They determine how our bodies are going to handle the medicines we take, and if those medicines are going to help us feel better or not. This research study includes testing the status of the CYP2D6 gene in children.