Primary Sclerosing Cholangitis

Also known as: PSC.

What is primary sclerosing cholangitis?

The bile ducts are channels that are responsible for carrying a digestive juice known as bile from the liver to the small intestine. In primary sclerosing cholangitis, the bile ducts narrow and harden due to inflammation and ultimately can cause serious liver damage.

What causes primary sclerosing cholangitis?

The exact cause of primary sclerosing cholangitis isn’t entirely clear. It’s often linked to other disease like inflammatory bowel disease. Other infections or toxins may cause the immune system to react and lead to primary sclerosing cholangitis.

What are the symptoms of primary sclerosing cholangitis?

Symptoms of primary sclerosing cholangitis can include abdominal pain, fever, chills, weight loss, fatigue, itchy skin and jaundice (yellowing of the skin and eyes), trouble absorbing nutrients and even cirrhosis/liver failure.

What are primary sclerosing cholangitis care options?

The only cure for primary sclerosing cholangitis is a liver transplant when possible. Other treatments involve managing symptoms and minimizing future liver damage with dietary changes, supplements and medications.

Reviewed by: Shifra A Koyfman, MD

This page was last updated on: March 20, 2019 04:07 PM