Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia
Conditions: B-cell Acute Lymphoblastic Leukemia (B-ALL)
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT02981628.
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Conditions: Leukemia
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT03959085.
Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation
Conditions: Leukemia
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT04203316.
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lympho
Conditions: Leukemia
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT04726241.
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma
Conditions: Glioma, Neurofibromatosis
Principal Investigator: Ziad Khatib
Learn more at https://clinicaltrials.gov/study/NCT03871257.
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
Conditions: Glioma, Astrocytoma
Principal Investigator: Ziad Khatib
Learn more at https://clinicaltrials.gov/study/NCT04166409.
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
Conditions: Non-germinomatous germ cell tumors (NGGCT)
Principal Investigator: Ziad Khatib
Learn more at https://clinicaltrials.gov/study/NCT04684368.
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Conditions: Osteosarcoma, Metastatic Malignant Neoplasm in the Lung
Principal Investigator: Ziad Khatib
Learn more at https://clinicaltrials.gov/study/NCT05235165.
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
Conditions: Germ Cell Tumor
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT03067181.
Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours (P3BEP)
Conditions: Germ Cell Tumor
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT02582697.
The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
Conditions: B-cell Acute Lymphoblastic Leukemia (B-ALL)
Principal Investigator: Jorge Galvez-Silva
Learn more at https://clinicaltrials.gov/study/NCT03509961.
Pediatric Precision Laboratory Advanced Neuroblastoma Therapy (PEDS-PLAN)
Conditions: Neuroblastoma
Principal Investigator: Guillermo De Angulo
Learn more at https://clinicaltrials.gov/study/NCT02559778.
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
Conditions: Langerhans Cell Histiocytosis
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT05828069.
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
Conditions: Wilms Tumor
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT04322318.
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
Conditions: Sarcoma
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT05304585.
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to
Conditions: Advanced or Metastatic Solid Tumor
Principal Investigator: Ossama Maher
Learn more at https://clinicaltrials.gov/study/NCT04142437.
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma
Conditions: Acute Lymphoblastic Leukemia (ALL)
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT05602194.
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
Conditions: Hodgkin's Lymphoma
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT05675410.
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
Conditions: Basal Ganglia Germinoma
Principal Investigator: Ziad Khatib
Learn more at https://clinicaltrials.gov/study/NCT06368817.
A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy
Principal Investigator: Ziad Khatib
Learn more at https://clinicaltrials.gov/study/NCT06413706.
Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma
Conditions: Neuroblastoma
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT05489887.
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
Conditions: Leukemia
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT05761171.
DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma
Conditions: Medulloblastoma
Principal Investigator: Ossama Maher
Learn more at https://clinicaltrials.gov/study/NCT04696029.
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
Conditions: Ganglioneruoblastoma, Neuroblastoma
Principal Investigator: Maggie Fader
Learn more at https://clinicaltrials.gov/study/NCT06172296.
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
Conditions: Leukemia, Myelodysplastic Syndrome
Principal Investigator: Jorge Galvez-Silva
Learn more at https://clinicaltrials.gov/study/NCT05457556.