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Blood and Marrow Transplantation Program

The Blood and Marrow Transplantation Program at Nicklaus Children's Hospital, formerly Miami Children's Hospital, is South Florida’s first and most experienced care provider for children requiring blood or bone marrow transplantation. Established in 1991, the program was originally accredited in 2003 by the Foundation for the Accreditation of Cellular Therapies (FACT) for all aspects of blood or marrow transplantation. The program continues to meet the rigorous FACT standards, having achieved its most recent reaccreditation in 2013. FACT accreditation is given to organizations that exceed standards in patient care and laboratory practices.

Excellent Outcomes Close to Home

The Blood and Marrow Transplant Program maintains outcomes that are the best in the region as reported by the National Marrow Donor Program (NMDP). The program’s experience and dedication to quality and in-depth staff training continues to drive outcomes that well exceed predicted outcomes.

Access to the Latest Research Protocols and Data

The Blood and Marrow Transplant Program is a Children’s Oncology Group (COG) accredited center for transplants and is a member of the Pediatric Blood and Marrow Transplant Consortium (PBMTC) and the International Blood and Marrow Transplant Registry (IBMTR). Membership in these organizations brings access to the very latest research protocols and national and international research data. Nicklaus Children's Hospital has also been designated a Blue Distinction Center for Transplants in the category of pediatric blood and marrow transplantation . The hospital is also an Optum Health Transplant Center of Excellence for blood and marrow transplants. 

Conditions Treated by a Blood and Marrow Transplantation Program at Nicklaus Children’s  

The program offers blood and marrow transplantation to treat the following conditions: 

A Full Spectrum of Transplant Options  

The Blood and Marrow Transplant Program at Nicklaus Children’s has the capability to conduct blood and marrow transplants from the patient’s own cells (an autologous transplant), as well as from blood or marrow from both related and unrelated donors (allogeneic transplant). The decision regarding the type of transplant that will be pursued for each patient, depends on the type of disease and its scope and the availability of the various donor sources.

The program has capability to conduct transplants utilizing bone marrow (soft tissue inside bones), peripheral blood (circulating blood) and/or cord blood (umbilical cord blood). Peripheral blood and bone marrow can be extracted via a needle procedure  Umbilical cord blood is donated by families of healthy newborns and collected at the time of their birth and frozen for a later use. To facilitate transplants from unrelated donors, the program has access to the National Marrow Donor Program (NMDP), enabling access to matched unrelated blood, marrow or cord blood units.  In some circumstances, cord blood from two separate donors can be combined to provide sufficient cord blood for a particular patient.

The Blood and Marrow Transplant Unit

The Blood and Marrow Transplant Unit is a private  unit within the hospital’s pediatric hematology-oncology wing that is made available exclusively for children undergoing blood and marrow transplantation. While in the unit, the child is in the care of a multidisciplinary team, including hematologist/oncologists, who are specially trained in blood and marrow transplantation, highly trained and experienced nurse practitioners, nursing and care coordination staff, as well as a social worker, psychologist, pharmacist, dietician, Child Life therapist, music therapist as well as physical and occupational therapists. The Child Life and music therapy staff help support the child’s developmental and recreational needs during hospitalization. 

Designated as a Blue Distinction Center for Transplants
Commission on Cancer
FACT Accredited

For more information about the Blood Marrow Transplant Program, or to make an appointment, please call (305) 663-6851 or toll free at

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