Lymphomas

Also known as: Hodgkin lymphoma, Hodgkin’s lymphoma, Hodgkin disease, Hodgkin’s disease, non-Hodgkin lymphoma, non-Hodgkin’s lymphoma, NHL

What are Lymphomas?

Lymphomas are a group of blood cell cancers/tumors that start in cells that are part of the body’s immune/lymphatic system (which play an important role in fighting off infection), that then multiply creating a tumor mass in the body. The tumor cells can spread to the rest of the body.

The two main groups of lymphoma are Hodgkin and non-Hodgkin forms (about 90% of cases). The World Health Organization includes two other categories as types of lymphomas: multiple myeloma and immunoproliferative disease.

There are many subtypes that can impact a child’s body, and the difference is related to the cells that are involved. Tumors and their cells can spread throughout the body through the lymph system as well as to other types of tissue within the body.

What causes lymphomas in children?

Lymphoma appears to be related to a genetic mutation. In some cases, this can be passed along from parents to children. Some environmental factors can increase one’s risk of getting lymphoma, such as certain viral diseases, problems with one’s immune system or exposure to radiation or other hazardous chemicals and medications.

What are the symptoms of lymphoma?

Signs and symptoms of lymphoma may include painless swelling of lymph nodes in one's armpits, neck or groin, fatigue, fever, night sweats, loss of appetite, and weight loss.

What are lymphoma care options?

Treatment may include one or more of the following: chemotherapy, radiation therapy and other drugs known as biological therapy (targeted therapy). Blood or bone marrow transplant is reserved for patients at high risk or those with recurrent disease.


Reviewed by: Jack Wolfsdorf, MD, FAAP

This page was last updated on: January 06, 2021 04:45 PM

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Hodgkin Lymphoma

Lymphoma is a type of cancer that affects the body’s lymphatic system (immune system). Usually the earliest sign of Hodgkin's lymphoma is an enlarged lymph node in the armpit, groin or neck. After that other nodes, the liver and the spleen become bigger. Learn more

Non-Hodgkin lymphoma

Non-Hodgkin lymphoma is an uncommon type of cancer in children. It starts in the body’s lymphatic system which are part of the body’s defenses against infections. Learn more

Radiation Therapy

Radiation therapy is a common form of cancer treatment. It refers to exposing the body to beams of radiation that are used to kill cancer cells and prevent them from coming back. Learn more

Blood and Marrow Transplantation

The transplantation of blood or bone marrow is the procedure of transferring and replacing the hematopietic stem cells. Learn more

Head and Neck Cancer and Tumor Surgery

In the pediatric population there are variety of tumors that can originate in the head and neck. Common tumors are lymphoma, salivary tumors and thyroid cancer. Learn more

Lymphography and Thoracic Duct Embolization

These are two different but related procedures that are used to treat problems with the thoracic duct. Lymphography is an imaging test, and thoracic duct embolization involves sealing off the thoracic duct when there are problems with it. Learn more