Also known as: Hodgkin lymphoma, Hodgkin’s lymphoma, Hodgkin disease, Hodgkin’s disease, non-Hodgkin lymphoma, non-Hodgkin’s lymphoma, NHL
What are Lymphomas?
Lymphomas are a group of blood cell cancers/tumors that start in cells that are part of the body’s immune/lymphatic system (which play an important role in fighting off infection), that then multiply creating a tumor mass in the body. The tumor cells can spread to the rest of the body.
The two main groups of lymphoma are Hodgkin and non-Hodgkin forms (about 90% of cases). The World Health Organization includes two other categories as types of lymphomas: multiple myeloma and immunoproliferative disease.
There are many subtypes that can impact a child’s body, and the difference is related to the cells that are involved. Tumors and their cells can spread throughout the body through the lymph system as well as to other types of tissue within the body.
What causes lymphomas in children?
Lymphoma appears to be related to a genetic mutation. In some cases, this can be passed along from parents to children. Some environmental factors can increase one’s risk of getting lymphoma, such as certain viral diseases, problems with one’s immune system or exposure to radiation or other hazardous chemicals and medications.
What are the symptoms of lymphoma?
Signs and symptoms of lymphoma may include painless swelling of lymph nodes in one's armpits, neck or groin, fatigue, fever, night sweats, loss of appetite, and weight loss.
What are lymphoma care options?
Treatment may include one or more of the following: chemotherapy, radiation therapy and other drugs known as biological therapy (targeted therapy). Blood or bone marrow transplant is reserved for patients at high risk or those with recurrent disease.
Reviewed by: Jack Wolfsdorf, MD, FAAP
This page was last updated on: January 06, 2021 04:45 PM
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Lymphoma is a type of cancer that affects the body’s lymphatic system (immune system). Usually the earliest sign of Hodgkin's lymphoma is an enlarged lymph node in the armpit, groin or neck. After that other nodes, the liver and the spleen become bigger.
Non-Hodgkin lymphoma is an uncommon type of cancer in children. It starts in the body’s lymphatic system which are part of the body’s defenses against infections.
Immune Deficiency Syndromes
Immune deficiency syndrome refers to a broad range of medical disorders that prevent your body from protecting itself from illnesses such as viruses and bacteria. There are a number of different types of congenital and acquired immune deficiency syndromes that can impact the body in a variety of ways.
Chemotherapy is a common form of cancer treatment. It refers to drugs that are often used to kill cancer cells and prevent them from coming back.
Radiation therapy is a common form of cancer treatment. It refers to exposing the body to beams of radiation that are used to kill cancer cells and prevent them from coming back.
Photopheresis is a medical procedure that can treat graft versus host disease. It involves suppressing the immune system to prevent it from reacting adversely on the skin.
Head and Neck Cancer and Tumor Surgery
In the pediatric population there are variety of tumors that can originate in the head and neck. Common tumors are lymphoma, salivary tumors and thyroid cancer.