Renal Parenchyma Diseases
Also known as: renal parenchymal diseases, renal parenchyma of the kidney, bilateral renal parenchyma diseases.
What are renal parenchyma diseases?
The renal parenchyma is the functional part of the kidney that includes the renal cortex (the outermost part of the kidney) and the renal medulla.
- The renal cortex contains the approximately 1 million nephrons (these have glomeruli which are the primary filterer of blood passing through the kidney, and renal tubules which modify the fluid to produce the appropriate amount/content of urine).
- The renal medulla consists primarily of tubules/ducts which are the beginning of the collecting system that allows the urine to flow onwards to being excreted.
Renal parenchyma disease describes medical conditions which damage these parts of the kidney. These diseases may be congenital, hereditary or acquired.
What causes renal parenchyma diseases?
Causes vary and include:
What are the signs/symptoms of renal parenchyma diseases?
As the kidneys regulate the amount of fluid in the body and adjust the salts in the blood to reflect metabolic activity, (plus other hormonal functions), common signs include:
- swelling of hands/feet/eyes (edema)
- high blood pressure
- bone changes
- blood in the urine
- abdominal swelling
Common symptoms include loss of appetite, itching, nausea and vomiting, fatigue, joint pain, frequent night urination and dizziness.
What are renal parenchyma diseases care options?
Treatments depends on the underlying cause and controlling that, plus alleviating symptoms and preventing complications are the focus of management.
Medications, fluid management, attention to calorie intake, dietary changes, dialysis and possibly kidney transplantation are all frequently utilized.
Reviewed by: Jack Wolfsdorf, MD, FAAP
This page was last updated on: September 15, 2020 09:32 AM
Learn more about
Polycystic Kidney Disease
PKD is a kidney disorder where numerous cysts enlarge in both kidneys reducing the amount of normal kidney tissue and thereby the kidney’s ability to function normally, leading to kidney failure.
A kidney stone is a solid, hard, pebble-like object that forms in a child’s kidneys when normal urine substances (like calcium, oxalates, magnesium and phosphorus) become very concentrated. There are 4 main types of kidney stones- those containing primarily calcium, cystine, uric acid or struvite.
Dialysis is a medical procedure that cleans and filters the body’s blood, either with a machine or the lining of the abdomen. It’s a procedure that is necessary in the case of kidney failure. The kidneys usually handle the task of cleaning the body’s blood.