What is Beckwith-Wiedemann Syndrome?
Beckwith-Wiedemann syndrome was first described by doctors Bruce Beckwith and Hans Rudolph Wiedemann in the 1960’s. The doctors identified children who had a number of symptoms including body overgrowth, external intestines, enlarged tongues, and low blood sugar. When a child exhibited all of these characteristics, they described them as having Beckwith-Wiedemann syndrome. Today, approximately 1 in 13,700 people have the condition.
What are its clinical characteristics?
What causes Beckwith-Wiedemann?
Beckwith-Wiedemann is a result of abnormal activity in the genes that regulate the body’s cell growth. While there is no single cause for the change of these genes, a geneticist can determine the source with special testing and evaluation. Most individuals with Beckwith-Wiedemann are the first affected in the family and the risk for recurrence is low. However, there may be a hereditary connection depending on the underlying cause.
What is the prognosis for my child with Beckwith-Wiedemann?
The prognosis for most children with this condition is generally positive, and treatment
varies by child. It is important to monitor your child’s tumor development, but most children with Beckwith-Wiedemann will attend school, have friends, and enjoy life. With close follow-up by the craniofacial team
and/or clinical geneticists at Nicklaus Children’s Hospital, your child can grow to become a healthy and happy adult.
Reviewed by: Chad Perlyn, MD
This page was last updated on: 6/21/2019 2:16:26 AM
Date: Friday, July 10, 2020
Nicklaus Children’s Hospital invites you to attend a conference designed to provide individuals with Beckwith-Wiedemann Syndrome (BWS) and their families with up-to-date information about the possible aspects of BWS and their management.