Also known as: Nuclear factor-kappa B Essential Modulator deficiency syndrome, NEMO deficiency syndrome.
What is NEMO syndrome?
NEMO syndrome is a rare genetic disease that impacts the immune system that predisposes the patient to frequent and serious infections, it also causes problems related to the skin, as well as the lungs, stomach and urinary tract in some instances.
What causes NEMO syndrome?
It is a genetic defect caused by a mutation in the Nuclear factor-kappa B Essential Modulator (NEMO) gene. Why this mutation occurs isn’t exactly clear.
What are the symptoms of NEMO syndrome?
The most common symptoms of NEMO syndrome include an inability to fight off diseases, thick skin, few sweat glands, abnormal teeth and thin hair. A number of other symptoms can occur in some instances.
What are NEMO syndrome care options?
Immunoglobulin therapy can help boost immunity in children with NEMO syndrome. Antibiotics and other medications may be needed to help the child fight infections. In severe cases, a stem cell transplant may help with the condition.
Reviewed by: Jose G. Calderon, MD
This page was last updated on: May 06, 2021 10:28 AM
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Immune Deficiency Syndromes
Immune deficiency syndrome refers to a broad range of medical disorders that prevent your body from protecting itself from illnesses such as viruses and bacteria. There are a number of different types of congenital and acquired immune deficiency syndromes that can impact the body in a variety of ways.
Blood and Marrow Transplantation
The transplantation of blood or bone marrow is the procedure of transferring and replacing the hematopietic stem cells.