Wiskott-Aldrich Syndrome

Also known as: WAS.

What is Wiskott-Aldrich syndrome?

Wiskott-Aldrich syndrome is a genetic disorder that affects the immune system and the blood coagulation system. It causes reduced immune function that predisposes the patient to infections, less ability to form blood clots, abnormal white blood cells and an increased risk of autoimmune disorders, among other complications.

What causes Wiskott-Aldrich syndrome? 
Wiskott-Aldrich syndrome is due to a genetic mutation. The disorder can be passed down from parents to their children. For this condition it is inherited from the mother and only boys are affected, girls do not have symptoms, they are healthy carriers of the genetic mutation.

What are the symptoms of Wiskott-Aldrich syndrome?
Due to reduced immunity, repeated and dangerous infections are a common symptom of Wiskott-Aldrich syndrome. The disease can also lead to the development of eczema, bleeding, and an increased risk of cancer or autoimmune diseases.

What are Wiskott-Aldrich syndrome care options? 
A stem cell transplant is the only potential cure for Wiskott-Aldrich syndrome. In most cases, the symptoms and infections need to be treated on a case by case basis as they arise.

Reviewed by: Jose G. Calderon, MD

This page was last updated on: 4/19/2018 3:09:36 PM



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