Also known as: MAS.
What is McCune-Albright syndrome?
McCune-Albright syndrome is a genetic disorder that impacts the bones, skin and endocrine system. The main characteristic is the development of scar-like tissue in the bones due to a condition called polyostotic fibrous dysplasia.
What causes McCune-Albright syndrome?
McCune-Albright syndrome is caused by genetic mutations. It is not passed down from parents to children but instead occurs randomly.
What are the symptoms of McCune-Albright syndrome?
The bone scarring that occurs with McCune-Albright syndrome often leads to uneven growth of bones, deformities and fractures. Problems with the face and a curved spine (scoliosis) are common. Skin patches called café-au-lait spots are common as are other symptoms related to the endocrine system disturbance such as rapid heart rate, high blood pressure, sweating and other symptoms.
What are McCune-Albright syndrome care options?
There is no cure for McCune-Albright syndrome. Treatment is focused on preventing problems or managing them as they occur through medications and surgery.
Reviewed by: Saoussen Salhi, MD
This page was last updated on: 8/16/2018 9:08:43 AM
From the Newsdesk
Dr. Chad Perlyn is a pediatric plastic surgeon with the Division of Plastic Surgery at Nicklaus Children's Hospital. For more information, please visit nicklauschildrens.org/Craniofacial
Following an emergency C-section, Gabriela’s mother, Katherine, was shocked to see that her new baby was missing part of her face. Gabriela was born with a cleft lip and palate. Katherine researched for hours to find the best doctors to fix her daughter’s condition and came upon the craniofacial team at Nicklaus Children’s Hospital.