Addison's Disease

Also known as: adrenal insufficiency.

What is Addison’s disease?

The adrenal glands produce steroid hormones (glucocorticoids-cortisol, and mineralocorticoids-aldosterone) that regulate many bodily functions, including the ability to respond to stress. When the adrenal glands produce insufficient amounts of these hormones, the disorder is known as Addison’s disease.
 

What causes Addison’s disease? 

Primary Addison’s disease most frequently results from damage to the adrenal glands by an autoimmune disease. Other causes include infections (like tuberculosis), adrenal hemorrhage, a genetic abnormality (rare), cancer, the long term use of steroids as a treatment for another condition (iatrogenic disease), some medications and by other diseases affecting either the adrenal glands or the function of the pituitary gland (Secondary or Central adrenal insufficiency).
 

What are the symptoms of Addison’s disease? 

Mild symptoms may only be seen when the child is physically stressed. Common symptoms of Addison’s disease include fatigue, weakness, weight loss, dehydration, decreased appetite, rapid pulse and a low blood pressure, salt craving, darkening of the skin particularly the hands and face, black freckles, nausea, vomiting, diarrhoea, abdominal pain, and intolerance to cold.
 

What are Addison’s disease care options? 

Treatment includes replacement of the essential deficient hormones (orally or intravenously) such as hydrocortisone and aldosterone (a hormone that helps restore stadium and potassium levels) and managing symptoms. 

Reviewed by: Jack Wolfsdorf, MD, FAAP

This page was last updated on: 3/23/2018 2:19:46 PM

From the Newsdesk

Diabetic children learn about nutrition and keeping healthy at Camp Roaring Sun
07/11/2018 — Camp Roaring Sun, which began Monday and runs through Friday, allowed children ages 6 through 12 to take part in traditional camp activities such as swimming, playing outside, and going to a baseball game. All the activities are monitored by Nicklaus pediatric endocrinology nurses to ensure a safe and healthy environment.
Meet Pedro Pagán, MD - The Division of Endocrinology at Nicklaus Children's Hospital
04/11/2018 — Dr. Pedro Pagán is employed by Pediatric Specialists of America (PSA), the physician-led multi-specialty group practice of Nicklaus Children's Health System. He is a pediatric endocrinologist within the Division of Pediatric Endocrinology at Nicklaus Children's Hospital and sees patients at Nicklaus Children's Hospital and the Nicklaus Children's Aventura Care Center. https://www.nicklauschildrens.org/endocrinology

Video

video
El Dr. Luis-Gonzalez Mendoza nos explica qué es la diabetes tipo 2 en los niños y las señales que se presentan para que podamos detectarla.