Also known as: Cobb syndrome
What is Cobb syndrome?
Cobb syndrome is a rare, non-inherited disorder characterized by visible skin lesions with underlying spinal angiomas or arteriovenous malformations (AVM).
The skin lesions typically are present as Port-Wine Stains
(light pink to dark purple birthmarks), but reports exist of angiokeratomas, angiolipomas, and lymphangioma circumscriptum.
The congenital cutaneous vascular lesions are usually distributed in a dermatomal pattern, from midline back to abdomen.
The underlying intraspinal lesions may be angiomas and AVMs at the same level of the spinal cord corresponding to the involved dermatomes of the skin. Patients typically present with a sudden onset of back or lower extremity radicular pain associated with numbness or, in some cases, paralysis.
Treatment for Cobb syndrome
Early intervention with spinal decompression is key to minimizing permanent neurological damage; thus, early correct diagnosis is of extreme importance.
A possible complication if treatment is delayed is Foix-Alajouanine disease which is a necrotic myelophathy due to thrombosis in the spinal angioma.
Patients displaying signs and symptoms of this disorder may undergo several imaging studies such as MRI
, Radiography, Angiography, and CT scans
, as well as a thorough work-up by specialists in the fields of Neurology
, and Interventional Radiology to ensure the best prognosis.
Come and learn about the diagnosis and treatment of vascular birthmarks and how we can help your child.
Learn more and register
Join us for a Live chat with Dr. Ana Duarte, Pediatric Dermatologist, Dr. Chad Perlyn, Pediatric Plastic Surgeon and Dr. Ricardo Restrepo, Pediatric Radiologist, who together are part of the comprehesive multi-specialty center for the evaluation and management of all birthmakrs, known as The International Birthmark Institute (TIBI) at Nicklaus Children's Hospital. Hear from these top doctors about what you and your families should know about birthmarks in this edition of Talkin' Kids Health.
Learn more and register
This page was last updated on: 3/23/2018 1:55:25 PM
From the Newsdesk
Just a few weeks after Brianna was born, her mother noticed a red growth on her daughter’s upper lip. Her pediatrician referred the family to specialists who diagnosed the growth as an Infantile Hemangioma. On December 7th, Dr. Chad Perlyn of Nickalus Children's Hospital, removed the hemangioma.
The Vascular Birthmarks Foundation presented Dr. Ana Duarte with a 2016 Physician of the Year Award for outstanding service in the diagnosis and treatment of children affected by a vascular birthmark.