Also known as: Cobb syndrome
What is Cobb syndrome?
Cobb syndrome is a rare, non-inherited disorder characterized by visible skin lesions with underlying spinal angiomas or arteriovenous malformations (AVM).
The skin lesions typically are present as Port-Wine Stains
(light pink to dark purple birthmarks), but reports exist of angiokeratomas, angiolipomas, and lymphangioma circumscriptum.
The congenital cutaneous vascular lesions are usually distributed in a dermatomal pattern, from midline back to abdomen.
The underlying intraspinal lesions may be angiomas and AVMs at the same level of the spinal cord corresponding to the involved dermatomes of the skin. Patients typically present with a sudden onset of back or lower extremity radicular pain associated with numbness or, in some cases, paralysis.
Treatment for Cobb syndrome
Early intervention with spinal decompression is key to minimizing permanent neurological damage; thus, early correct diagnosis is of extreme importance.
A possible complication if treatment is delayed is Foix-Alajouanine disease which is a necrotic myelophathy due to thrombosis in the spinal angioma.
Patients displaying signs and symptoms of this disorder may undergo several imaging studies such as MRI
, Radiography, Angiography, and CT scans
, as well as a thorough work-up by specialists in the fields of Neurology
, and Interventional Radiology to ensure the best prognosis.
This page was last updated on: 3/23/2018 1:55:25 PM
From the Newsdesk
In observance of vascular birthmarks awareness month, The International Birthmarks Institute at Nicklaus Children’s Hospital held its first Vascular Birthmarks Conference at the hospital’s main campus on May 5th. The event brought together patients, families and medical professionals representing a range of specialties to present the latest in diagnosis, treatment and research related to birthmarks.
Just a few weeks after Brianna was born, her mother noticed a red growth on her daughter’s upper lip. Her pediatrician referred the family to specialists who diagnosed the growth as an Infantile Hemangioma. On December 7th, Dr. Chad Perlyn of Nickalus Children's Hospital, removed the hemangioma.