Our Biobank Samples
The Nicklaus Children's Biobank has the ability to collect blood samples (store extracted DNA) and data from a participant over time and to include samples from both the proband and family members is highly significant in terms of the ability of the Biobank to support studies focused on personalized and translational medicine. The Biobank will also collect, process, and store remnant and archived clinical material (tissue and fluids – FFPE & Archival tissue services), and specimens collected specifically for research purposes (tissue and fluids). Samples may be used immediately, further processed (into DNA, cell lines, etc.), and/or stored for future use. It is anticipated that the exact procedures for aliquoting, processing, and storage will vary over time so that the Biobank can optimize the mix of samples and matrices to match evolving research needs.
Sample integrity is essential to the success of every research project. Various Pre and Post-analytical variables can be introduced at numerous points in a sample, beginning at the time it is collected, through transport, receiving, laboratory processing, during storage and subsequent retrieval for analysis. For the Nicklaus Children's Biobank, providing high quality samples is our goal.
Our Biobank Services
Nicklaus Children's Biobank operates to national and international standards. All biospecimens are validated against original pathological diagnosis to confirm accuracy and assure high quality standards. Nicklaus Children's Biobank supports research by ensuring investigators have access to high quality samples annotated with clinical data.
Nicklaus Children's Biobank provides services in:
- baking of samples,
- procurement, processing, archiving, and distribution of fresh and formalin-fixed tissues and body fluids,
- specimen characterization, quality control, and linkage with pathological and clinical annotation,
- auxiliary services including histology, immunohistochemistry, whole blood DNA Extraction, and computer-assisted imaging/image analysis.
Our Biobank is designed to support the biospecimen handling requirements of any local or multi-institutional research study, biobanking, or clinical trial with full integration into our Clinical Trial Management System.
- Access to Banked samples
- Modular collection kits for biospecimen collection that allow for standardized collection and specimen annotation from on and off-site locations
- Body fluid processing and aliquoting
- Surgical specimen procurement by specialized staff stationed in the pathology suite
- Tissue fixation and embedding
- Specimen archiving and inventory
- Distribution of specimen and associated data for research projects
- Provide remnant archival material from surgical pathology specimens for research projects
- Imaging and image analysis (Aperio XT and Syncroscopy tissue imaging system)
Please contact us to discuss your project; our services can be tailored to meet the needs for individual collections and research projects at email@example.com. Pricing available upon request.
How to Apply
- Fill out the RedCap form
- With your project information and detailed sample request. You will also be required to submit the Curriculum vitae of Principal Investigator (no longer than 2 pages) and IRB approval and amendment letters (or equivalent).
- We also recommend you read the Nicklaus Children’s Biobank Conditions of Use.
- We will review your application and provide a feasibility assessment in 5-7 business days.
- You will receive letter of approval, plus work order. Upon approval, your project will commence! Any subsequent de-identified clinical data will be securely transferred to you and samples will be shipped expeditiously.
Please contact us to discuss your project. Our services can be tailored to meet the needs for individual collections and research projects at firstname.lastname@example.org – Pricing available upon request.