Larsen Syndrome

Also known as: LS

What is Larsen syndrome?

Larsen syndrome is a rare genetic disorder that babies can be born with. It primarily affects the structure and development of bones, but it can vary widely in its presentation. Common symptoms of Larsen syndrome include clubfeet, scoliosis, a greater range of joint movement than usual (hypermobility) and other abnormalities.

What causes Larsen syndrome?
A genetic mutation causes Larsen syndrome. This can occur spontaneously or be passed down from parents to children.

What are the symptoms of Larsen syndrome?
Symptoms of Larsen syndrome can vary widely from person to person. They typically all involve joint or skeletal abnormalities. Possible symptoms include:
  • Cleft palate
  • Short fingers and toes
  • Short stature
  • Distinctive facial features
  • A curved spine
  • Clubfeet
  • Extra bones in the ankles and wrists
  • Other abnormalities


What are Larsen syndrome care options?

Treatments for Larsen syndrome are focused on managing specific symptoms and helping individuals with the disease live the best life possible. Different forms of therapy can help with managing the condition, and corrective surgery may be a possibility for some complications of Larsen syndrome.

Reviewed by: Scott J Schoenleber, MD

This page was last updated on: 8/7/2018 9:37:30 AM

From the Newsdesk

Haley's Success Story
Growing up, Haley Gantt suffered from scoliosis. She had to wear a back brace to prevent her curve from worsening, but unfortunately, she was later told that a spinal fusion surgery would have to be considered because the brace had failed to prevent the curve from progressing. She fought hard and got through it. An accomplished basketball player, Haley is now on her way to playing Division II basketball for Biola University in Southern California.
April Patient of the Month: Lucky
Lucky started going to physical therapy when he was two because of the delays with sitting up and rolling over. His physical therapist noticed that the problem was not muscular but skeletal, a condition that she couldn't treat. The pediatrician told Janie and Greg, Lucky’s parents, about Nicklaus Children's Hospital. When Janie and Greg visited Nicklaus Children’s Hospital, they met Dr. Harry L Shufflebarger, Pediatric Spinal Surgery Director. He performed the necessary surgeries and now Lucky can enjoy a healthy life.

Video

video
When should bracing be used as a treatment for idiopathic scoliosis?