Larsen Syndrome

Also known as: LS

What is Larsen syndrome?

Larsen syndrome is a rare genetic disorder that babies can be born with. It primarily affects the structure and development of bones, but it can vary widely in its presentation. Common symptoms of Larsen syndrome include clubfeet, scoliosis, a greater range of joint movement than usual (hypermobility) and other abnormalities.


What causes Larsen syndrome?

A genetic mutation causes Larsen syndrome. This can occur spontaneously or be passed down from parents to children.


What are the symptoms of Larsen syndrome?

Symptoms of Larsen syndrome can vary widely from person to person. They typically all involve joint or skeletal abnormalities. Possible symptoms include:
  • Cleft palate
  • Short fingers and toes
  • Short stature
  • Distinctive facial features
  • A curved spine
  • Clubfeet
  • Extra bones in the ankles and wrists
  • Other abnormalities


What are Larsen syndrome care options?

Treatments for Larsen syndrome are focused on managing specific symptoms and helping individuals with the disease live the best life possible. Different forms of therapy can help with managing the condition, and corrective surgery may be a possibility for some complications of Larsen syndrome.

Upcoming Events

Beckwith-Wiedemann Syndrome (BWS) Family Conference

Nicklaus Children’s Hospital invites you to attend a conference designed to provide individuals with Beckwith-Wiedemann Syndrome (BWS) and their family’s up-to-date information about the possible aspects of BWS and their management. 

Learn more and register

Reviewed by: Scott J Schoenleber, MD

This page was last updated on: 3/23/2018 2:15:37 PM

From the Newsdesk

Sports Health Center at Pinecrest
04/17/2018 — The Sports Health Center at Pinecrest is designed to help the young athletes in our community when it comes to prevention and rehabilitation of sports injuries.
April Patient of the Month: Lucky
04/09/2018 — Lucky started going to physical therapy when he was two because of the delays with sitting up and rolling over. His physical therapist noticed that the problem was not muscular but skeletal, a condition that she couldn't treat. The pediatrician told Janie and Greg, Lucky’s parents, about Nicklaus Children's Hospital. When Janie and Greg visited Nicklaus Children’s Hospital, they met Dr. Harry L Shufflebarger, Pediatric Spinal Surgery Director. He performed the necessary surgeries and now Lucky can enjoy a healthy life.