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Also known as: MAS.
McCune-Albright syndrome is a genetic disorder that impacts the bones, skin and endocrine system. The main characteristic is the development of scar-like tissue in the bones due to a condition called polyostotic fibrous dysplasia.
McCune-Albright syndrome is caused by genetic mutations. It is not passed down from parents to children but instead occurs randomly.
The bone scarring that occurs with McCune-Albright syndrome often leads to uneven growth of bones, deformities and fractures. Problems with the face and a curved spine (scoliosis) are common. Skin patches called café-au-lait spots are common as are other symptoms related to the endocrine system disturbance such as rapid heart rate, high blood pressure, sweating and other symptoms.
There is no cure for McCune-Albright syndrome. Treatment is focused on preventing problems or managing them as they occur through medications and surgery.
This page was last updated on: September 12, 2019 03:16 PM
Date: Saturday, July 11, 2020
The Nicklaus Children's Family Conference 2020 is going virtual! Please register online for access to lectures and Q&A Sessions.