Tenosynovial Giant Cell Tumor

Also known as: TGCT

What are tenosynovial giant cell tumors?

A tenosynovial giant cell tumor is a benign (non-cancerous) tumor that can impact the soft tissue around the joints of bones. Though they are non-cancerous and don’t spread to other parts of the body, they can still grow quickly and cause complications.

What causes tenosynovial giant cell tumors?

Like most forms of cancer, tenosynovial giant cell tumors develop due to changes in a cell’s DNA. Why these changes occur, however, isn’t clear.

What are the symptoms of tenosynovial giant cell tumors?

Possible symptoms of tenosynovial giant cell tumors include a noticeable bump, pain and swelling at the joint, as well as stiffness, heat or warmth at the joint, a catching or popping sensation at the joint or joint instability or weakness.

How can tenosynovial giant cell tumors affect children?

Tenosynovial giant cell tumors are much more common in adults than they are in children. Presentation and treatment in children is similar to adults.

What are tenosynovial giant cell tumor treatments?

Tenosynovial giant cell tumors are most commonly removed with surgery. In some instances, chemotherapy can be used to shrink and destroy the benign tumors.

Reviewed by: Maggie Fader, MD

This page was last updated on: November 02, 2023 03:41 PM