Hgb H Constant Spring

Also known as: hemoglobin H – constant spring.

What is Hgb H constant spring?

Hgb H disease is a form of alpha thalassemia, a medical condition in which the body makes less hemoglobin than usual. It causes anemia. There are four genes that contribute to the making of hemoglobin. When a person is missing three of these genes, the body makes an abnormal form of hemoglobin known as hemoglobin H. Hemoglobin H – constant spring is a particular severe form of Hgb H disease that can cause of number of problems.

What causes Hgb H constant spring?

Hgb H constant spring is a genetic disease, and the abnormal genes are passed along from parents to their children. Parents are missing one or two genes and the child receives only one gene.

What are the symptoms of Hgb H constant spring?

Possible symptoms of Hgb H constant spring include:

What are Hgb H constant spring care options?

Hgb H constant spring can be severe. Many people with the disease require regular blood transfusions and iron chelation in order to live a healthy life.


Reviewed by: Athena Pefkarou, MD

This page was last updated on: September 30, 2020 11:52 AM

Sickle Cell / Hemoglobinopathies Care Program

For over 30 years we've strived to offer a comprehensive, patient family focused health care delivery system that integrates local community resources.

Learn more

Learn more about

Gallstones and Gallbladder

The gallbladder is a pear-shaped organ attached to the liver that stores bile. Gallstones are abnormal solid deposits made of cholesterol and biliary pigments. They are found inside the gallbladder. Learn more

Alpha Thalassemia

Alpha thalassemia is an abnormality in the production of alpha chains which causes the red cells to more easily breakdown. Learn more

Iron Chelation Therapy

Iron chelation therapy is a treatment used to remove excess iron from the blood. Learn more

Blood Transfusions

A blood transfusion is when blood is infused into the body to replace missing blood. Learn more