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Also known as: Hemoglobin C trait.
Hemoglobin is the protein in the blood that carries oxygen from the lungs throughout the body. One abnormal form of hemoglobin is known as hemoglobin C. When a person has hemoglobin C trait, they have some hemoglobin C, but much more normal hemoglobin (hemoglobin A). This does not cause any health problems, but they can pass along hemoglobin C to their children. This differs from hemoglobin C disease, which leads to anemia and causes red blood cells to break down earlier than normal.
Hgb C trait occurs when one parent passes along the gene for hemoglobin C disease to a fetus, and the other parents pass along a gene for normal hemoglobin. A person with Hgb C trait can potentially pass the abnormal gene along to his or her children.
People with Hgb C trait do not have the symptoms related to hemoglobin C disease, such as anemia.
No treatment is necessary for individuals with Hgb C trait.
Reviewed by: Athena Pefkarou, MD
This page was last updated on: July 05, 2022 02:05 PM
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Hemoglobin C can cause red blood cells to break down earlier than normal, which leads to anemia. Learn more