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Nicklaus Children’s Hospital has several outpatient and urgent care centers throughout South Florida, including on-demand, virtual care.
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Also known as: hemoglobin C disease.
Hemoglobin is the protein in the blood that carries oxygen from the lungs throughout the body. One abnormal form of hemoglobin is known as hemoglobin C, and it can cause red blood cells to break down earlier than normal, which leads to anemia. This condition is known as hemoglobin C disease, or Hgb C disease.
Hgb C disease is a genetic disorder that is passed along from parents to their children. It’s a recessive genetic disorder, which means that both parents must pass along the trait in order for the child to develop the disorder.
The primary symptom of Hgb C disease is a low blood count or anemia, which typically doesn’t cause other symptoms. Other possible complications include low red blood cell count during infection or illness, enlarged spleen, joint pain and an increased risk of gallstones or infections.
This is a mild hemolytic anemia with no serious complications and treating them as they arise. Treatments typically involve preventing potential complications and treating them as they arise.
Reviewed by: Athena Pefkarou, MD
This page was last updated on: April 11, 2022 03:57 PM
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Anemia is a disorder in which the body doesn’t have enough red blood cells. Hemolysis is a method whereby red blood cells are broken down and destroyed. Would you like to learn about more ways to get involved at Nicklaus Children's?*
When a person has hemoglobin C trait, they have some hemoglobin C, but much more normal hemoglobin (hemoglobin A). Would you like to learn about more ways to get involved at Nicklaus Children's?*