Scientific Focus

Technology Assessment

The HOPE Center conducts diagnostic performance studies to determine the sensitivity, specificity and receiver operating characteristic (ROC) curves of emerging technologies. Intra and interobserver variability of new diagnostic and therapeutic test are also evaluated.

Decision Analysis Studies

Decision Analysis studies are those structured to assess a specific clinical question or problem over time, by creating a decision tree that illustrates sequential choice points for action and for information gathering, and when specific outcomes occur. The flow of the decision tree information is based on the available literature. Decision Analysis studies determine the best choice of diagnostic tests or treatments for specific diseases.

Error Prevention and Quality Improvement System

Medical error is one of the seven leading causes of death in the United States of America. The HOPE Center emphasizes the use of computerized simulators and education as important tools in the prevention of medical error and the improvement of our patient's quality of care.

Cost-Effectiveness Analysis

Cost-effectiveness analysis (CEA) provides information so society can prioritize the use of our limited healthcare resources. Ideally, CEA should be done from a societal prospective with long-term outcomes such as life years saved, or quality-adjusted life years saved. These long-term CEA outcomes allow comparison of different health care diagnostic studies and interventions.

Evidence-based Medicine and Imaging

The physicians and the medical staff should base medical decisions and actions on the best scientific evidence available. The HOPE Center performs extensive literature review, operational and research studies to provide our patients with the most updated medical information. Guidelines and decision trees are developed to optimize the diagnostic and therapeutic strategies for our patients.