Also known as: Pediatric hepatoblastoma, childhood liver cancer.

What is hepatoblastoma?

A hepatoblastoma is a rare tumor that grows from the cells of the liver. It’s the most common of liver cancers in childhood, occurring during the first 18 months of life (infants to 5 years of age), in mostly white children, boys, and those born prematurely of low birth weight.

What causes hepatoblastoma? 

While the cause is unknown, certain genetic (familial adenomatous polyposis, Beckwith-Wiedemann syndrome) and other medical conditions can put children at a greater risk of getting hepatoblastoma (e.g. hemihyperplasia, hepatitis B infection, biliary atresia).

What are the signs/symptoms of hepatoblastoma?

Signs and symptoms depend on the size of the tumor and whether or not it has spread. They include:

  • a lump in the liver
  • a swollen abdomen
  • fever
  • weight loss
  • vomiting
  • reduced appetite
  • jaundice with yellow skin and eyes
  • itchiness and/or pale skin color (anemia)
  • back pain

What are hepatoblastoma care options?

Treatments include surgery and one or more types of chemotherapy.

Reviewed by: Jack Wolfsdorf, MD, FAAP

This page was last updated on: March 31, 2022 03:51 PM

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