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► Hemophagocytic lymphohistiocytosis (HLH)

Hemophagocytic lymphohistiocytosis (HLH)

Also known as: HLH

Hemophagocytic lymphohistiocytosis (HLH)

Hemophagocytic lymphohistiocytosis is a life-threatening inherited condition of the immune system. Immune system cells, principally T cells and NK cells are unable to perform their function of destroying infected or damaged cells. The immune system begins to damage healthy tissue of the organs, bone marrow, liver and brain.
Treatment: Treatment includes steroid therapy as well as chemotherapy to destroy the damaged cells. Blood and marrow transplantation is reserved for select HLH patients with for HLH patients with recurrent or residual disease, or for those with genetic changes.

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