Marcos Mestre, MD - Pediatric Hospitalist

A clinician identified with a Nicklaus Children’s Pediatric Specialists logo is an affiliate of Nicklaus Children's Health System. All other clinicians listed on the website are in independent medical practices.

Marcos Mestre, MD, FAAP, FHM, MBA
Vice President and Chief Medical Officer
Nicklaus Children's Hospital

Dr. Marcos Mestre serves as vice president and chief medical officer (CMO) for Nicklaus Children’s Hospital, a nationally recognized nonprofit pediatric specialty hospital based in Miami, Florida and the flagship campus of Nicklaus Children’s Health System, the region’s only healthcare system exclusively for children.

In his role, Dr. Mestre oversees the medical affairs and operations of the 309-bed Nicklaus Children’s Hospital and its network of pediatric outpatient centers situated in Miami-Dade, Broward, Martin and Palm Beach counties. He serves as a collaborative dyad leader, along with the hospital’s chief nursing officer (CNO), responsible for ensuring patients receive high quality, coordinated care throughout their health journey. As a board-certified practicing physician in general pediatrics and pediatric hospital medicine, Dr. Mestre supports the well-being of Nicklaus Children’s patients in both administrative and clinical roles.

Dr. Mestre has over 15 years of clinical practice and medical staff leadership experience. Most recently, he served as the section chief and division director of Hospital Medicine at Nicklaus Children’s Hospital, where he was also the senior medical director of Pediatric Services for Nicklaus Children’s Pediatric Specialists, a nonprofit physician practice subsidiary of Nicklaus Children’s Health System. Prior to Nicklaus Children’s, Dr. Mestre practiced as a hospitalist physician for a private physician practice in Miami, Florida. He is a fellow of the American Academy of Pediatrics (AAP) and a clinical assistant professor at the Florida International University Herbert Wertheim College of Medicine.

Dr. Mestre is a graduate of the University of Miami, where he earned a bachelor’s degree with honors in Biology and Psychology and an executive master’s degree in Business Administration in Health Sector Management and Policy. He earned his medical degree from the University of Florida College of Medicine and completed his residency at the University of North Carolina (UNC) Hospitals in Chapel Hill.

Montarroyos, S.S., Franyie Ladd, B., Mestre, M., et al (2023). Classification of SARS-CoV-2 Pediatric Hospitalizations: Delta vs Omicron Variant. Hospital pediatrics, 13(10), 940-944. View in Pubmed

Gill, P.J., Mahant, S., ..., Mestre, M., et al (2022). Association Between Corticosteroids and Outcomes in Children Hospitalized With Orbital Cellulitis. Hospital Pediatrics, 1(12), 70-89. View in Pubmed

House, S.A., Hall, M., ..., Mestre, M., et al (2021). Development and Use of a Calculator to Measure Pediatric Low-Value Care Delivered in US Children's Hospitals. JAMA Network open, 14(12), e2135184. View in Pubmed

Payson, A., Etinger, V., ..., Mestre, M. (2021). Risk of Serious Bacterial Infections in Young Febrile Infants With COVID-19. Pediatric Emergency Care, 37(4), 232-236. View in Pubmed

Clark, N.A., Rodean, J., Mestre, M., et al (2021). Pandemic-Related Shifts in New Patients Admitted to Children's Hospitals. Hospital Pediatrics, 11(8), e142-e151. View in Pubmed

Goenka, P.K., Hall, M., ..., Mestre, M., et al (2021). Corticosteroids in the Treatment of Pediatric Retropharyngeal and Parapharyngeal Abscesses. Pediatrics, 148(5), 2020037010. View in Pubmed

Keren, R., Shah, S.S., Srivastava, R., et al (2015). Comparative effectiveness of intravenous vs oral antibiotics for postdischarge treatment of acute osteomyelitis in children. JAMA pediatrics, 169(2), 120-128. View in Pubmed

Reyes, M., Mestre, M. (2007). Denial or Restriction of Hospital Privileges for Hospitalists. Hospital pediatrics,

Primary Office

Nicklaus Children's Hospitalist Services
3100 SW 62 Ave -Main Bldg-3rd Flr - Hospitalist
Miami, FL 33155
Phone Number:


Residency - University of North Carolina
Medical School - Unversity of Florida, Shands

Board Certifications

American Board of Pediatrics (Pediatric Hospital Medicine) - Certified
American Board of Pediatrics (Pediatrics) - Certified