Also known as: CN, cyclic neutropenia, periodic neutropenia, cyclic hematopoiesis
What is cyclic neutropenia?
Neutrophils (or white blood cells) are one type of body cell that fights infection. Children with cyclic neutropenia (usually diagnosed in their first year of life) have a fairly non-serious disease (benign) where their white blood cell count becomes low for 3-5 days, every 14-35 days. During each of these times they are susceptible to bacterial and viral infections.
What causes cyclic neutropenia?
Cyclic neutropenia is an inherited genetic disorder where one copy of the abnormal gene passed down from a parent is enough to cause the disease (autosomal dominant pattern). (New gene abnormality -mutations- with no family history also occur and can result in the disorder).
What are the symptoms of cyclic neutropenia?
Recurrent fevers, sore gums and throat, respiratory and skin infections, sinus problems, and ulcers in the mouth and colon.
What are cyclic neutropenia care options?
Appropriate antibiotics to treat bacterial infections. Other drugs to increase the production of neutrophils may be tried.
Reviewed by: Jack Wolfsdorf, MD, FAAP
This page was last updated on: 5/23/2018 10:36:05 AM
The Nicklaus Children’s Cancer & Blood Disorders Center, together with the Brain Institute is proud to host this free event designed to deliver education, support and guidance for children diagnosed with brain tumors and their caregivers. Learn more.
In this edition of Talkin' Kids Health we will discuss cancer effects and the survivorship program at Nicklaus Children's with Dr. Haneen Abdella, Pediaric Oncolgoist at Nicklaus Children's and Kristen Mendez, ARNP and Manager of the Survivorship Program. Learn more.
From the Newsdesk
Children with SCD may present anemia, repeated infections, and shortness of breath.
Children with Leukemia can have different oral manifestations.
At just 16 years old, Raquel was diagnosed with Pre-B acute lymphoblastic leukemia. She first noticed something was wrong in the summer of 2015 when she realized she had swollen glands behind her ear.