Microcystic Adnexal Carcinoma

Also known as: MAC

What is microcystic adnexal carcinoma?

Microcystic adnexal carcinoma is a rare cancer that forms in the sweat glands. It typically develops in the head, neck or face, although the trunk, extremities and genitals are other potential areas where it can develop.

What causes microcystic adnexal carcinoma?

Like most forms of cancer, microcystic adnexal carcinoma develops due to changes in a cell’s DNA. What specifically causes these changes to occur isn’t clear. Ultraviolet radiation exposure (sunlight), previous radiation therapy and immunosuppressive medications are potential risk factors.

What are the symptoms of microcystic adnexal carcinoma?

Microcystic adnexal carcinoma often becomes visible on the skin as the cancer grows. A white or pink plaque on the face or trunk is the typical presentation of the disease.

How can microcystic adnexal carcinoma affect children?

Microcystic adnexal carcinoma is rare in children but has been documented occasionally. The presentation in children is similar to adults.

What are microcystic adnexal carcinoma treatments?

Surgical removal of the tumor and the surrounding tissue is the typical treatment for microcystic adnexal carcinoma. Chemotherapy and radiation therapy may also be recommended in some instances.

Reviewed by: Maggie Fader, MD

This page was last updated on: November 03, 2023 12:21 PM