MIAMI, FL AND ALACHUA, FL – Miami Children’s Hospital, recognized by U.S. News & World Report for excellence in 10 pediatric subspecialties in 2011 and 2012, and AxoGen, Inc. have announced the hospital’s first nerve repair surgery with Avance® Nerve Graft. The processed nerve allograft technology was implanted during a surgery recently to repair a brachial plexus injury suffered by a 6 month-old baby girl.
The surgery was performed by Dr. John A. I. Grossman, MD, FACS, Director of The Brachial Plexus Program at Miami Children’s Hospital, Clinical Associate Professor of Orthopedic Surgery at New York University’s School of Medicine, author of numerous studies on pediatric brachial plexus repair and an associate editor of the Journal of Brachial Plexus and Peripheral Nerve Injury. “The Avance® Nerve Graft is changing how we approach the surgical reconstruction of injured brachial plexus nerves and is a very valuable new tool,” offered Dr. Grossman.
The brachial plexus controls the movement of muscles and sensation in the shoulder, arm and hand. Brachial plexus injuries may occur if an infant’s neck is excessively stretched during birth or by traumatic injury. If left untreated, brachial plexus birth injuries can have lifelong consequences including paralysis or limited movement, numbness and weakness in the shoulder, arm, hand and fingers.
Dr. Grossman, who works at both Miami Children’s Hospital and NYU Hospital for Joint Diseases, runs one of the busiest programs in the country for treating these types of injuries. Depending on the severity of the injury, treatment often involves surgical repair and replacement of injured or torn nerves. Historically, healthy nerve was taken from elsewhere in the patient’s body and used to repair the damaged nerve in a procedure known as an autograft. Limitations in the amount of healthy nerve available for grafting created a market need for a nerve substitute. Dr. Grossman added, “Avance® Nerve Graft is the closest you can get to the patient’s own nerve in terms of structure, size and compatibility with the body’s healing processes. The technology also assures that we will have enough graft material to complete a successful surgical repair.”
AxoGen’s Chief Executive Officer, Karen Zaderej, noted, “With over 4 years of clinical use of our Avance® Nerve Graft in the United States and thousands of implantations, we often hear from surgeons and patients about their recovery journeys. We are pleased that this young patient can benefit from our technology.”
About AxoGen, Inc.
AxoGen (AXGN.OB) is a regenerative medicine company with a portfolio of proprietary products and technologies for peripheral nerve reconstruction and regeneration. Every day, people suffer traumatic injuries or undergo surgical procedures that impact the function of their peripheral nerves. Peripheral nerves provide the pathways for both motor and sensory signals throughout the body and their damage can result in the loss of function and feeling. In order to improve surgical reconstruction and regeneration of peripheral nerves, AxoGen has developed and licensed patented and patent-pending technologies, which are used in its portfolio of products. This portfolio includes Avance® Nerve Graft, the only commercially available allograft nerve for bridging nerve discontinuities (a gap created when the nerve is severed) of 5mm to 70mm in length. AxoGen’s portfolio also includes AxoGuard® Nerve Connector, a coaptation aid allowing for close approximation of severed nerves gaps up to 5mm in length, and AxoGuard® Nerve Protector, a bioscaffold used to reinforce a coaptation site, wrap a partially severed nerve or isolate and protect nerve tissue.
AxoGen brings the science of nerve repair to life with thousands of surgical implants of AxoGen products and technology performed in hospitals and surgery centers across the United States, including military hospitals serving U.S. service men and women.
AxoGen is the parent of its wholly owned operating subsidiary, AxoGen Corporation. AxoGen’s principal executive office and operations are located in Alachua, FL.
About Nicklaus Children’s Hospital
Founded in 1950 by Variety Clubs International, Nicklaus Children's Hospital is South Florida's only licensed specialty hospital exclusively for children, with nearly 800 attending physicians and more than 475 pediatric subspecialists. The 309-bed hospital, known as Miami Children's Hospital from 1983 through 2014, is renowned for excellence in all aspects of pediatric medicine with many specialty programs routinely ranked among the best in the nation by U.S. News & World Report since 2008. The hospital is also home to the largest pediatric teaching program in the southeastern United States and has been designated an American Nurses Credentialing Center (ANCC) Magnet facility, the nursing profession’s most prestigious institutional honor. For more information, please visit www.nicklauschildrens.org.