What is Cobb syndrome?

Also known as: Cobb syndrome

Cobb syndrome is a rare, non-inherited disorder characterized by visible skin lesions with underlying spinal angiomas or arteriovenous malformations (AVM). The skin lesions typically are present as Port-Wine Stains (light pink to dark purple birthmarks), but reports exist of angiokeratomas, angiolipomas, and lymphangioma circumscriptum.

The congenital cutaneous vascular lesions are usually distributed in a dermatomal pattern, from midline back to abdomen. The underlying intraspinal lesions may be angiomas and AVMs at the same level of the spinal cord corresponding to the involved dermatomes of the skin. 

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This page was last updated on: 1/29/2019 3:21:13 PM