What is CLOVES syndrome?

Also known as: CLOVE syndrome, CS, congenital lipomatous overgrowth, vascular malformations, epidermal nevis and scoliosis/skeletal/spinal anomalies.

CLOVES syndrome is a very rare disorder, one of a group of congenital (present at birth) “overgrown syndromes”, that is characterized by the presence of several problems together. CLOVES stands for:

  • Congenital
  • Lipomatous
  • Overgrowth
  • Vascular
  • Epidermal Nevis
  • Spinal / Skeletal / Anomalies / Scoliosis

This disorder includes: large collections (masses) of fatty tissue, complex vascular malformations, patches of overgrown skin, spine problems, other bone and joint abnormalities and stiff or weak muscles.


Reviewed by: Jack Wolfsdorf, MD

This page was last updated on: 1/29/2019 3:21:13 PM

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