Cancer Center | Nicklaus Children's Hospital

Sarcoma and Limb Salvage Program

Our Sarcoma and Limb Salvage Program provides care for children with any type of bone cancer.

For tumors involving the musculoskeletal system, Nicklaus Children's Orthopedic Surgery Program offers full evaluation and treatment, including prescribing and interpreting imaging and testing, as well as performing biopsies and definitive cancer surgery treatment. The orthopedic surgical team enlists one of the region’s most experienced oncological orthopaedists to remove pediatric tumors and reconstruct extremities utilizing the most advanced limb salvage techniques available. The team is one of a few in the region to utilize oncological prostheses for limb salvage that make it possible for a child’s leg to grow through a series of nonsurgical adjustments, eliminating the need for future leg-lengthening surgeries. The department also coordinates rehabilitative care of the patient following cancer surgery.

Bone Cancer in Children

There are three types of primary bone cancer (cancer that arises in the bone, as opposed to cancer that spreads to the bone from another part of the body, which is referred to as secondary bone cancer).

  • Osteosarcoma, the most common in children, which develops in new tissue in growing bones, usually in the knees, upper legs and upper arms.
  • Ewing's sarcoma begins in immature nerve tissue in bone marrow.
  • Chondrosarcoma arises in cartilage, usually in the pelvis, upper legs and shoulders, and occurs more often in adults.

Clinical Trials

Nicklaus Children’s Cancer Center is participating in a clinical trial of an investigational drug in children with metastatic tumors in the Ewing’s sarcoma family.

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Lacy's Success Story
At only 2 years old, Lacy needed to have a tumor removed from her brain; she also went through six months of chemotherapy and a stem cell transplant. Today, Lacy is cancer free and going to different therapies to continue getting stronger every day.

Designated as a Blue Distinction Center for Transplants


Recognized by the American College of Surgeons Commission on Cancer


Accredited by the Foundation for the Accrediation of Cellular Therapies (FACT)