Genetic/Metabolic Diseases of the Liver

Also known as: inherited metabolic disease of the liver.

What are genetic/metabolic diseases of the liver?

Certain disorders that children are born with can make it difficult for the liver to process certain nutrients, such as fats, proteins or carbohydrates. This group of disorders is known as genetic/metabolic diseases of the liver. Some of the names of these disorders include but are not limited to Wilson’s disease, Alpha-1 Antitrypsin deficiency, GALD (Gestational Alloimmune Liver Disease), fatty acid oxidation defects, glycogen storage deficiencies, galactosemia, lipid storage diseases, tyrosinemia, urea cycle disorders, and peroxisomal disorders.

What causes genetic/metabolic diseases of the liver?

As the name suggests, these disorders are due to a genetic mutation that a child is born with.

What are the symptoms of genetic/metabolic diseases of the liver?

Symptoms can vary depending on the nature of the condition. Symptoms can affect the liver and include nausea, vomiting, fatigue, weight loss, pain, bloating, jaundice, other symptoms, and at times liver failure. Symptoms can also impact other parts of the body depending on the nature of the disorder.

What are genetic/metabolic diseases of the liver care options?

The common treatments for genetic/metabolic diseases of the liver can include dietary changes, medications, and, in extreme cases, a liver transplant.


Reviewed by: John M. Peters, DO

This page was last updated on: 3/23/2018 2:09:24 PM

From the Newsdesk

Medical Mission to Algeria Helps Children in Need of Spinal Surgeries
03/06/2018 — A group of children in Algeria who underwent complex surgeries as part of a 2016 U.S.-sponsored medical mission have many reasons to celebrate, and can do so with better movement of their limbs.
Outpatient Surgery Success Story
02/28/2018 — Caludell noticed that 6 of her 11 children had belly buttons that stuck out, and they seemed to become more pronounced around the time they entered kindergarten. When her daughters started to become self-concious about how their belly buttons looked, Claudell was able to schedule all 6 umbilical repair surgeries on the same day at the Miami Children's  Ambulatory Surgery Center.