Van der Woude Syndrome

Also known as: VDWS.

What is Van der Woude syndrome?

Van der Woude syndrome is a genetic disorder that affects the mouth and face. The most common symptoms are cleft lip, cleft palate, depressions (pits) or extra tissue on the lower lip and missing teeth on occasion.

What causes Van der Woude syndrome? 
Van der Woude syndrome occurs due to a genetic mutation, and it can be passed along from an affected person to their children. The condition can also occur for the first time in a person.

What are the symptoms of Van der Woude syndrome?
The facial differences are the primary symptoms of Van der Woude syndrome. Children with the condition may have developmental delays or learning disabilities, as well.

What are Van der Woude syndrome care options? 
Various surgical procedures can be used to correct  the facial differences that arise as part of Van der Woude syndrome.

Reviewed by: Mislen S Bauer, MD

This page was last updated on: 4/6/2018 9:03:29 AM

Upcoming Events

Beckwith-Wiedemann Syndrome (BWS) Family Conference

Nicklaus Children’s Hospital invites you to attend a conference designed to provide individuals with Beckwith-Wiedemann Syndrome (BWS) and their family’s up-to-date information about the possible aspects of BWS and their management. 

Learn more and register

From the Newsdesk

Movie Event Celebrates Children with Craniofacial Differences
04/30/2018 — Children who receive care at the Craniofacial Center at Nicklaus Children’s, along with their families, enjoyed an afternoon of red carpet glamour and photo booth fun on April 28. 
March Patient of the Month: Theodore
03/15/2018 — Meet our March Patient of the Month, Theodore. Theodore was diagnosed with cleft palate, cleft lip and a heart problem when he was only 18 weeks old. After he was born, Theodore had to be admitted into the NICU to be able to perform the necessary surgeries for him to live a healthy life.


Dr. Chad Perlyn, pediatric plastic surgeon, talks about the different types of tongue reduction operations for BWS.