Multiple Endocrine Neoplasia Type 2
Also known as: MEN2, MEN 2A syndrome, MEN 2B syndrome.
What is multiple endocrine neoplasia type 2?
Multiple endocrine neoplasia type 2 is a disease that affects several glands throughout the body, including the thyroid, parathyroid and adrenal gland. It causes tumors in these glands and also imbalances in the hormones that the glands produce. It differs from multiple endocrine neoplasia type 1 based on the genetic mutation that causes it, and some of the glands that it impacts.
What causes multiple endocrine neoplasia type 2?
Multiple endocrine neoplasia type 2 is the result of a genetic mutation. The disease is passed down from parents to children.
What are the symptoms of multiple endocrine neoplasia type 2?
The tumors that are typical of multiple endocrine neoplasia type 2 lead to hormone imbalances, which in turn produce symptoms such as kidney stones, bone loss, bone pain, constipation, indigestion, fatigue and other symptoms. Though the tumors are usually benign, they can increase the risk of cancer developing over time.
What are multiple endocrine neoplasia type 2 care options?
Surgery to remove the tumor is often the recommended treatment for multiple endocrine neoplasia type 2. Medications can also help with many of the symptoms related to the disease.
Close follow up and monitoring with blood tests and ultrasound and MRI is essential to detect any tumor at an early stage.
Reviewed by: Ziad A Khatib, MD
This page was last updated on: 5/23/2018 3:00:13 PM
The Adolescent and Young Adult (AYA) Program at the Nicklaus Children's Cancer Center invites oncology patients 14 years of age and older to this fun event. Food and beverages will be provided. Learn more.
From the Newsdesk
The Nicklaus Children's Hospital biobank and tissue repository is an essential resource for personalized medicine research efforts, enabling the study of both health and disease over time. The Biobank collects samples and health information from volunteers, regardless of health history. Once a participant becomes part of the Biobank, he or she contributes to ongoing health research. We partner with Sanford Health, a national leader on specimen storage, management and integration with participant health information.
When Layla was 5, she came to Nicklaus Children's Hospital with a severe case of scoliosis. To help straighten her spine, Layla spent time in halo gravity traction. While her mom returned home to Gainesville for work and school, the nurses at Nicklaus Children's took care of Layla, acting as substitute mothers and making sure she was well cared for.