Also known as: Vitamin B12 deficiency anemia, folate-deficiency anemia, folic acid deficiency anemia, pernicious anemia.
What is megaloblastic anemia?
Megaloblastic anemia is a type of anemia where the bone marrow produces fewer and abnormally large, oval shaped (instead of round/disk-like) red blood cells, with underdeveloped inside contents (hemoglobin). They tend not to survive as long as normal red blood cells.
What causes megaloblastic anemia?
There are many causes (e.g. congenital abnormalities of absorption, abnormalities of the bowel like celiac disease, certain medications that interfere with vitamin absorption etc.), however the most common cause in children is a deficiency of folic acid or Vitamin B-12.
What are the symptoms of megaloblastic anemia?
Common symptoms include:
- Pale skin
- Poor appetite
- Smooth and painful tongue
- Stomach problems
- Numbness/tingling in hands and feet
- Difficulty walking
- Muscle weakness
- Fast/irregular heartbeat
- Trouble breathing and
- Lightheadedness or dizziness
What are megaloblastic anemia care options?
Depending on a number of factors, the typical treatment includes treating the underlying cause, administration of a folic acid (by mouth for 2-3 months) supplement or vitamin B-12 (by injection) and modifying the child's diet to include foods that contain significant amounts of folic acid and Vitamin B-12.
Reviewed by: Jack Wolfsdorf, MD, FAAP
This page was last updated on: 5/23/2018 2:51:44 PM
The Adolescent and Young Adult (AYA) Program at the Nicklaus Children's Cancer Center invites oncology patients 14 years of age and older to this fun event. Food and beverages will be provided. Learn more.
From the Newsdesk
The Nicklaus Children's Coconut Creek Care Center, located at 6370 North State Road 7 provides subspecialty consultations for babies, children, teens and young adults under 21 years of age. Board-certified physicians, employed by Pediatric Specialists of America, provide pediatric subspecialty care in the areas of: endocrinology, gastroenterology, orthopedics, spinal care, and plastic and reconstructive surgery.
For more information, please visit nicklauschildrens.org/coconutcreek.
Doctors in South Florida are performing a life-saving procedure for children born with a rare genetic condition: thalassemia.