Chronic Myelogenous Leukemia
Also known as: chronic myeloid leukemia, CML
What is chronic myelogenous leukemia?
Chronic myelogenous leukemia (CML) is a rare cancer of the blood in children where over time, too many immature white blood cells (granulocytes) form because of an abnormality in the normal maturation process of the cell. These young cells collect in large numbers in the bone marrow and crowd out other needed cells with a variety of side effects.
What causes chronic myelogenous leukemia?
CML arises because a piece of chromosome 22 breaks off and switches with a piece of chromosome 9 (Philadelphia chromosome). This changes the position and function of some genes that then gives rise to the cancer.
What are the signs/ symptoms of chronic myelogenous leukemia?
Signs/Symptoms of CML can include tiredness, weakness, night sweats, swollen lymph glands, easy brushing, fever, bone and joint pain, weight loss, stomach pain or a feeling of fullness/pain in the abdomen (because of large numbers of abnormal cells in the kidneys, liver and spleen).
What are chronic myelogenous leukemia care options?
Treatments depend on a number of different factors. The cancer specialists
at Nicklaus Children's Cancer Center
will fully discuss with you the various treatment options available and outline the resources which will help you and your family successively achieve the best possible outcome.
Reviewed by: Jack Wolfsdorf, MD, FAAP
This page was last updated on: 5/23/2018 10:31:28 AM
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Meet our July Patient of the Month, Lacy. Lacy was only 2 years old when her parents noticed that something was wrong. They took her to various doctors to try to find what could be the cause, Lacy had an 8 cm. tumor in her brain, occupying most of the lower part of her head.
From the Newsdesk
Children being treated by the Cancer & Blood Disorders Center, Neuro Oncology Program at Nicklaus Children’s Hospital and their families took part in a holiday celebration.
Dr. Toba N. Niazi, Neurosurgeon, and Dr. Ziad A. Khatib, Hematologist and Oncologist, discuss the second leading cause of cancer in children, brain tumors.