Also known as: PVL
What is periventricular leukomalacia?
Periventricular leukomalacia is a brain disorder occurring in babies (particularly premature babies) characterized by brain damage with softening (malacia) and death of the inner part of the brain (white matter).
What causes periventricular leukomalacia?
The exact cause of PVL is unknown but appears to result from too little blood/oxygen getting to that part of the brain. Very premature babies (born at 30 weeks or less of gestation) are more likely to get periventricular leukomalacia; as are those who have had a hemorrhage inside the brain, or whose mothers membranes (amniotic sac) have ruptured early or where there has been infection in the uterus.
What are the symptoms of periventricular leukomalacia?
Symptoms in infants vary widely. Mild cases may have no symptoms, others may only present with symptoms months after birth. The most common symptom is cerebral palsy which results in stiff, tight muscles particularly in the legs, movement, developmental and learning difficulties. Other symptoms may include vision and hearing loss, trouble with coordination and other impairments.
What are periventricular leukomalacia care options?
While there is no specific treatment for periventricular leukomalacia, disease management is focused on providing specialised care which might include physical therapy, occupational therapy, speech therapy, vision treatments and other specialized therapies as required.
Reviewed by: Jack Wolfsdorf, MD, FAAP
This page was last updated on: 6/12/2018 10:20:11 AM
This one day course will include educational sessions, case studies, and panel discussions that highlight evidence-based information for managing Autism Spectrum Disorders (ASD) and other related disabilities for children ages birth to 5. Learn more.
The Nicklaus Children’s Cancer & Blood Disorders Center, together with the Brain Institute is proud to host this free event designed to deliver education, support and guidance for children diagnosed with brain tumors and their caregivers. Learn more.
Weekly Support Programs
Participants will learn to optimize neurological potential across the developing age and care continuum, to provide other treatment modalities to optimize results, to provide options for our patients and families, to provide options for our patients and families, and more! Learn more.
From the Newsdesk
Children with Seizures can present many dental problems due to the oral side effects of the seizure medications.
Meet Nao Sasaki, MD of Nicklaus Children's Hospital, a pediatric cardiologist with The Heart Program.
What was supposed to be a fun day for Frankie and his sister with their uncle quickly took an unexpected and tragic turn. Frankie was kicked in the head by a horse at the ranch they were visiting, and he suffered a traumatic brain injury.