Also known as: cerebellar primitive neuroectodermal tumor, PNET.
What is medulloblastoma?
Of cancerous brain tumors that can affect children, medulloblastoma is the most common. They represent about 20 percent if childhood brain tumors, particularly in children between the ages of 3 and 8 years, with boys affected more than girls. Medulloblastomas form at the bottom of the brain in an area called the posterior fossa (the area of the brain that controls balance, coordination and other functions), and tends to spread through the fluid that surrounds the brain and spinal cord (cerebrospinal fluid-CSF) to other parts of the brain and the spinal cord.
What causes medulloblastoma?
While the cause is largely unknown. gene mutations or other genetic conditions such as Li-Fraumeni syndrome or Gorlin syndrome increase risk. In rare cases it can be passed down from parents to children.
What are the symptoms of medulloblastoma?
Symptoms of medulloblastoma can include behavioral problems, changes in handwriting, clumsiness or balance problems, nausea, vomiting, vision problems, headaches, tilting of the head. If in the spinal cord, back pain, bladder and bowel problems and trouble walking may be presenting symptoms.
What are medulloblastoma care options?
Treatments include neurosurgery used to remove as much of the tumor as possible, radiation therapy, chemotherapy, proton therapy and new biological agents to target specific mutations in these tumors.
Reviewed by: Jack Wolfsdorf, MD, FAAP
This page was last updated on: 7/12/2018 1:33:16 PM
The Adolescent and Young Adult (AYA) Program at the Nicklaus Children's Cancer Center invites oncology patients 14 years of age and older to this fun event. Food and beverages will be provided. Learn more.
Weekly Support Programs
This program is provided by a certified yoga instructor. It offers children and teens the following benefits: managing stress through breathing, self-awareness, healthy movement and meditation. Yoga also promotes strength, flexibility, coordination and body awareness. Learn more.
From the Newsdesk
Dr. John Ragheb, Director of the Division of Neurosurgery at Nicklaus Children’s Hospital, is among a group of renowned physicians who developed the first evidence-based guideline in the U.S. on mild traumatic brain injury (mTBI) and concussions among children, published by the CDC in September.
Dr. Aaron Berger is a pediatriac hand surgeon at Nicklaus Children's Hospital. For more information about the Brachial Plexus and Peripheral Nerve Disorders Program, please visit nicklauschildrens.org/BrachialPlexus