Gliomatosis Cerebri

Also known as: infiltrative diffuse astrocytosis, malignant astrocytic tumor.

What is gliomatosis cerebri?

Astrocytes are star-shaped cells that are part of a glial network of supportive and nourishing tissue within the brain. One rare form of malignant (cancerous) tumor that grows and infiltrates aggressively (grade 1V, the most malignant form of brain tumor) from these cells and which spreads over the top and throughout the brain is known as gliomatosis cerebri.
 

What causes gliomatosis cerebri? 

The cause of gliomatosis cerebri is unknown.
 

What are the symptoms of gliomatosis cerebri?

Symptoms of gliomatosis cerebri depend on what parts of the brain are affected and include:
  • Signs of raised pressure in the brain (seizures, nausea, vomiting, drowsiness, headaches)
  • Personality and behavioral changes
  • Localized symptoms (like weakness on one side of the body)
  • Problems with speech, memory or vision
  • Endocrine abnormalities
 

What are gliomatosis cerebri care options? 

Gliomatosis cerebri is difficult to remove surgically because it spreads throughout the brain. Radiation therapy, chemotherapy, as well one or more drugs in combination, are possible options of treatment. 

Reviewed by: Jack Wolfsdorf, MD, FAAP

This page was last updated on: 6/12/2018 10:00:22 AM


Upcoming Events

2018 Pediatric Autism Symposium: Ensuring Long Term Outcomes in Children Birth to Five

This one day course will include educational sessions, case studies, and panel discussions that highlight evidence-based information for managing Autism Spectrum Disorders (ASD) and other related disabilities for children ages birth to 5.

Learn more and register

Communication and Feeding Difficulties in Children with Autism Spectrum Disorders (ASD)

This class is offered to parents and caregivers of children diagnosed with Autism Spectrum Disorders.

Learn more and register

Camp UOTS

Camp U.O.T.S. is an annual weeklong, overnight camp for children with cancer and blood disorders who are treated at Nicklaus Children’s Hospital.

Learn more and register

Epilepsy Exchange

Join us for a Facebook Live event! The webinar will explore epilepsy treatment options including medications, surgeries and therapies, provide advice on how to choose a course of treatment and will include a live Q&A session. Join Patricia Dean, Aileen Marie Rodriguez, Drs. Ian Miller and Marytery Fajardo.

Learn more and register

From the Newsdesk

Siblings of Cancer Patients enjoy a Fun Filled Day
07/06/2018 — More than two dozen children attended the Bear Hug camp at Nicklaus Children's last week. This day camp is for siblings of pediatric cancer patients to encourage socialization among peers and help them gain insight on their siblings' care journey. 
Get your FREE Water Watcher Card here!
06/29/2018 — Prevent drowning and accidents when children are near water by assigning a responsible adult to wear a Water Watcher Badge. The badge wearer takes responsibility to supervise the children until hading off to the next water watcher. Available at selected urgent care centers while supplies last.

Video

video
Toba Niazi, MD of Nicklaus Children's Hospital is a pediatric neurosurgeon with the Brain Institute.