Hgb H Disease
Also known as: hemoglobin H disease.
What is Hgb H disease?
Hemoglobin H disease is a form of alpha thalassemia, a medical condition in which the body makes less hemoglobin than usual. There are four genes that contribute to the making of hemoglobin. When a person has a problem with three of these genes, the body begins to make an abnormal form of hemoglobin known as hemoglobin H, which can cause blood flow problems and anemia.
What causes Hgb H disease?
Hemoglobin H is a genetic disease, and the abnormal genes are passed along from parents to their children. A person must receive the genes from both parents in order to develop Hgb H disease.
What are the symptoms of Hgb H disease?
Possible symptoms of Hgb H disease include anemia, jaundice, gallstones, growth retardation and an increased risk of infections.
What are Hgb H disease care options?
Hgb H disease can be severe. Many people with the disease require regular blood transfusions and iron chelation in order to live a healthy life.
Reviewed by: Athena Pefkarou, MD
This page was last updated on: 10/29/2018 10:21:21 AM
From the Newsdesk
Doctors in South Florida are performing a life-saving procedure for children born with a rare genetic condition: thalassemia.
Dr. Jorge Galvez Silva is a pediatric hematologist/oncologist with the Cancer & Blood Disorders Center at Nicklaus Children's Hospital. For more information, please visit nicklauschildrens.org/cancer